STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zgc:64051Tetraspanin. (221 aa)    
Predicted Functional Partners:
clk2a
CDC-like kinase 2a.
      
 0.743
ccdc90b
Coiled-coil domain-containing 90B.
      
 0.670
agxta
Serine--pyruvate aminotransferase.
   
  
 0.565
mibp2
Muscle-specific beta 1 integrin-binding protein 2.
   
  
 0.542
agxtb
Serine--pyruvate aminotransferase.
   
  
 0.484
ndufa11
NADH:ubiquinone oxidoreductase subunit A11.
      
 0.483
psmb9a
Proteasome subunit beta.
   
  
 0.467
cyba
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
  
 0.414
actc1a
Actin, alpha, cardiac muscle 1a.
   
  
 0.412
thbs4b
Thrombospondin-4-B; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions and may be involved in various processes including cellular proliferation, migration, adhesion and attachment. May play a role in ER stress response (By similarity); Belongs to the thrombospondin family.
      
 0.402
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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