node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dkc1 | fbl | ENSDARP00000007628 | ENSDARP00000070509 | Dyskeratosis congenita 1, dyskerin. | Fibrillarin. | 0.999 |
dkc1 | gar1 | ENSDARP00000007628 | ENSDARP00000101401 | Dyskeratosis congenita 1, dyskerin. | H/ACA ribonucleoprotein complex subunit 1; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.999 |
dkc1 | mrto4 | ENSDARP00000007628 | ENSDARP00000002982 | Dyskeratosis congenita 1, dyskerin. | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.877 |
dkc1 | nhp2 | ENSDARP00000007628 | ENSDARP00000091811 | Dyskeratosis congenita 1, dyskerin. | H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.999 |
dkc1 | nip7 | ENSDARP00000007628 | ENSDARP00000076524 | Dyskeratosis congenita 1, dyskerin. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.889 |
dkc1 | nop10 | ENSDARP00000007628 | ENSDARP00000132783 | Dyskeratosis congenita 1, dyskerin. | H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.999 |
dkc1 | nop56 | ENSDARP00000007628 | ENSDARP00000099474 | Dyskeratosis congenita 1, dyskerin. | NOP56 ribonucleoprotein homolog. | 0.999 |
dkc1 | nop58 | ENSDARP00000007628 | ENSDARP00000131046 | Dyskeratosis congenita 1, dyskerin. | NOP58 ribonucleoprotein homolog (yeast). | 0.999 |
dkc1 | tert | ENSDARP00000007628 | ENSDARP00000124988 | Dyskeratosis congenita 1, dyskerin. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.992 |
dkc1 | wrap53 | ENSDARP00000007628 | ENSDARP00000105980 | Dyskeratosis congenita 1, dyskerin. | WD repeat-containing, antisense to TP53. | 0.997 |
fbl | dkc1 | ENSDARP00000070509 | ENSDARP00000007628 | Fibrillarin. | Dyskeratosis congenita 1, dyskerin. | 0.999 |
fbl | gar1 | ENSDARP00000070509 | ENSDARP00000101401 | Fibrillarin. | H/ACA ribonucleoprotein complex subunit 1; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.996 |
fbl | mrto4 | ENSDARP00000070509 | ENSDARP00000002982 | Fibrillarin. | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.931 |
fbl | nhp2 | ENSDARP00000070509 | ENSDARP00000091811 | Fibrillarin. | H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.999 |
fbl | nip7 | ENSDARP00000070509 | ENSDARP00000076524 | Fibrillarin. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.945 |
fbl | nop10 | ENSDARP00000070509 | ENSDARP00000132783 | Fibrillarin. | H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). | 0.983 |
fbl | nop56 | ENSDARP00000070509 | ENSDARP00000099474 | Fibrillarin. | NOP56 ribonucleoprotein homolog. | 0.999 |
fbl | nop58 | ENSDARP00000070509 | ENSDARP00000131046 | Fibrillarin. | NOP58 ribonucleoprotein homolog (yeast). | 0.999 |
fbl | tert | ENSDARP00000070509 | ENSDARP00000124988 | Fibrillarin. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.461 |
fbl | wrap53 | ENSDARP00000070509 | ENSDARP00000105980 | Fibrillarin. | WD repeat-containing, antisense to TP53. | 0.600 |