node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abcb7 | gfer | ENSDARP00000085602 | ENSDARP00000093302 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Sulfhydryl oxidase. | 0.764 |
atp23 | chchd4a | ENSDARP00000087721 | ENSDARP00000039846 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | 0.949 |
atp23 | chchd4b | ENSDARP00000087721 | ENSDARP00000128972 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Coiled-coil-helix-coiled-coil-helix domain-containing 4b. | 0.653 |
atp23 | cox17 | ENSDARP00000087721 | ENSDARP00000119424 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae). | 0.688 |
atp23 | cycsb | ENSDARP00000087721 | ENSDARP00000034555 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.459 |
atp23 | gfer | ENSDARP00000087721 | ENSDARP00000093302 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Sulfhydryl oxidase. | 0.825 |
atp23 | timm10 | ENSDARP00000087721 | ENSDARP00000091094 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.843 |
atp23 | timm50 | ENSDARP00000087721 | ENSDARP00000048422 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.529 |
chchd10 | chchd4a | ENSDARP00000005265 | ENSDARP00000039846 | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | 0.882 |
chchd10 | cox17 | ENSDARP00000005265 | ENSDARP00000119424 | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae). | 0.449 |
chchd10 | cycsb | ENSDARP00000005265 | ENSDARP00000034555 | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.436 |
chchd10 | gfer | ENSDARP00000005265 | ENSDARP00000093302 | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | Sulfhydryl oxidase. | 0.724 |
chchd10 | timm13 | ENSDARP00000005265 | ENSDARP00000075599 | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | Mitochondrial import inner membrane translocase subunit Tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of some prot [...] | 0.407 |
chchd4a | atp23 | ENSDARP00000039846 | ENSDARP00000087721 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. | 0.949 |
chchd4a | chchd10 | ENSDARP00000039846 | ENSDARP00000005265 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Coiled-coil-helix-coiled-coil-helix domain-containing 10. | 0.882 |
chchd4a | cox17 | ENSDARP00000039846 | ENSDARP00000119424 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae). | 0.990 |
chchd4a | cycsb | ENSDARP00000039846 | ENSDARP00000034555 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). | 0.817 |
chchd4a | gfer | ENSDARP00000039846 | ENSDARP00000093302 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Sulfhydryl oxidase. | 0.994 |
chchd4a | timm10 | ENSDARP00000039846 | ENSDARP00000091094 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.964 |
chchd4a | timm13 | ENSDARP00000039846 | ENSDARP00000075599 | Mitochondrial intermembrane space import and assembly protein 40; Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes (By similarity). Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitoc [...] | Mitochondrial import inner membrane translocase subunit Tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of some prot [...] | 0.798 |