STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sp5aSp5 transcription factor a. (368 aa)    
Predicted Functional Partners:
zfand6
Zinc finger, AN1-type domain 6.
      
 0.662
lef1
Lymphocyte enhancer binding factor 1 Lef1.
   
 
 0.568
emc6
ER membrane protein complex subunit 6; Belongs to the EMC6 family.
    
 
 0.553
pde9a
Phosphodiesterase.
    
 
 0.484
mmgt1
Membrane magnesium transporter 1; Mediates Mg(2+) transport.
      
 0.481
her5
Hairy-related 5.
   
 
 0.481
htr1ab
5-hydroxytryptamine (serotonin) receptor 1A b.
      
 0.480
emc1
ER membrane protein complex subunit 1.
      
 0.479
tmc4
Transmembrane channel-like protein.
    
 
 0.461
slc25a46
Solute carrier family 25 member 46; May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
      
 0.453
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.