STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zyg11Protein zyg-11 homolog; Serves as substrate adapter subunit in an E3 ubiquitin ligase complex zyg11-cul2-elongin BC. Targets substrates bearing N-terminal glycine degrons for proteasomal degradation. (746 aa)    
Predicted Functional Partners:
cul2
Cullin 2; Belongs to the cullin family.
   
 0.912
eloca
Elongin C paralog a; Belongs to the SKP1 family.
    
 
 0.749
elocb
Elongin C paralog b; Belongs to the SKP1 family.
    
 
 0.749
zer1
Zyg-11-related, cell cycle regulator.
   
 
0.742
fem1c
Protein fem-1 homolog C; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit; Belongs to the fem-1 family.
     
 0.587
appbp2
Amyloid beta precursor protein (cytoplasmic tail)-binding protein 2.
   
 
 0.558
ENSDARP00000134209
Si:ch1073-82l19.1.
  
  
 
0.550
zswim8
Zinc finger, SWIM-type-containing 8.
     
  0.540
zswim5
Zinc finger, SWIM-type-containing 5.
   
 
  0.540
zswim6
Zinc finger, SWIM-type-containing 6.
     
  0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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