STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lin52Protein lin-52 homolog. (112 aa)    
Predicted Functional Partners:
lin37
Lin-37 DREAM MuvB core complex component.
    
 0.999
lin54
Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA; Belongs to the lin-54 family.
    
 0.999
lin9
Protein lin-9 homolog; Belongs to the lin-9 family.
    
 0.999
mybl2b
V-myb avian myeloblastosis viral oncogene homolog-like 2b.
    
 0.995
rbbp4
Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.
   
 0.990
rbb4l
Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.
   
 0.971
foxm1
Forkhead box M1.
     
 0.953
e2f4
E2F transcription factor 4.
    
 0.944
tesmin
Testis-expressed metallothionein-like protein.
    
 
 0.938
rbl2
Retinoblastoma-like 2 (p130).
   
 0.930
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (74%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.