STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edn1Endothelin 1. (188 aa)    
Predicted Functional Partners:
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
ednrab
Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
ednrba
Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.
    
 0.997
ednrbb
Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.
    
 0.997
ece1
Endothelin-converting enzyme 1.
     
 0.957
ece2b
Endothelin-converting enzyme 2b.
     
 0.942
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.868
agtr2
Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.843
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
  
 0.832
agt
Angiotensinogen; Belongs to the serpin family.
     
 0.767
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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