node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
asic1a | asic2 | ENSDARP00000011782 | ENSDARP00000122509 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | 0.517 |
asic1a | gak | ENSDARP00000011782 | ENSDARP00000111020 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Cyclin G-associated kinase. | 0.580 |
asic1a | kcnj1a.1 | ENSDARP00000011782 | ENSDARP00000058986 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Potassium inwardly rectifying channel subfamily J member 1a, tandem duplicate 1. | 0.543 |
asic1a | kcnk2b | ENSDARP00000011782 | ENSDARP00000046437 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.525 |
asic1a | p2rx3a | ENSDARP00000011782 | ENSDARP00000019781 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | 0.602 |
asic1a | p2rx4a | ENSDARP00000011782 | ENSDARP00000108004 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | 0.650 |
asic1a | stom | ENSDARP00000011782 | ENSDARP00000120230 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Stomatin. | 0.611 |
asic1a | stoml3a | ENSDARP00000011782 | ENSDARP00000107042 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Stomatin (EPB72)-like 3a. | 0.615 |
asic1a | stoml3b | ENSDARP00000011782 | ENSDARP00000121180 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Stomatin (EPB72)-like 3b. | 0.611 |
asic1a | trpv1 | ENSDARP00000011782 | ENSDARP00000115992 | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | Transient receptor potential cation channel, subfamily V, member 1; Belongs to the transient receptor (TC 1.A.4) family. | 0.541 |
asic2 | asic1a | ENSDARP00000122509 | ENSDARP00000011782 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | 0.517 |
asic2 | gak | ENSDARP00000122509 | ENSDARP00000111020 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Cyclin G-associated kinase. | 0.580 |
asic2 | stom | ENSDARP00000122509 | ENSDARP00000120230 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Stomatin. | 0.611 |
asic2 | stoml3a | ENSDARP00000122509 | ENSDARP00000107042 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Stomatin (EPB72)-like 3a. | 0.611 |
asic2 | stoml3b | ENSDARP00000122509 | ENSDARP00000121180 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Stomatin (EPB72)-like 3b. | 0.611 |
asic2 | trpv1 | ENSDARP00000122509 | ENSDARP00000115992 | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | Transient receptor potential cation channel, subfamily V, member 1; Belongs to the transient receptor (TC 1.A.4) family. | 0.594 |
gak | asic1a | ENSDARP00000111020 | ENSDARP00000011782 | Cyclin G-associated kinase. | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | 0.580 |
gak | asic2 | ENSDARP00000111020 | ENSDARP00000122509 | Cyclin G-associated kinase. | Acid-sensing ion channel 2; Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. | 0.580 |
kcnj1a.1 | asic1a | ENSDARP00000058986 | ENSDARP00000011782 | Potassium inwardly rectifying channel subfamily J member 1a, tandem duplicate 1. | Acid-sensing ion channel 1A; Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. | 0.543 |
kcnj1a.1 | kcnk2b | ENSDARP00000058986 | ENSDARP00000046437 | Potassium inwardly rectifying channel subfamily J member 1a, tandem duplicate 1. | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.484 |