STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lnx2bLigand of numb-protein X-like protein. (678 aa)    
Predicted Functional Partners:
dharma
Dharma.
      
 0.850
e4f1
Transcription factor E4F1; May function as a transcriptional repressor. May also function as a ubiquitin ligase. Functions in cell survival and proliferation through control of the cell cycle.
    
 
 0.746
ved
Ventrally-expressed dharma/bozozok antagonist.
      
 0.744
vox
Ventral homeobox.
    
 
 0.704
numb
NUMB endocytic adaptor protein.
   
 
 0.652
numbl
NUMB-like endocytic adaptor protein.
   
 
 0.652
vent
Ventral-expressed homeobox.
   
  
 0.647
chic1
Novel protein similar to vertebrate cysteine-rich hydrophobic domain 1 (CHIC1).
      
 0.646
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
   
  
 0.623
pdzrn4
PDZ domain-containing ring finger 4.
    
 
 0.577
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: very high (100%) [HD]