STRINGSTRING
dstyk protein (Danio rerio) - STRING interaction network
"dstyk" - Dual serine/threonine and tyrosine protein kinase in Danio rerio
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dstykDual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death (By similarity). Plays a role in the embryonic development (885 aa)    
Predicted Functional Partners:
TMEM81
Si-dkey-48j7.3; Transmembrane protein 81 (259 aa)
           
  0.817
tmcc2
Transmembrane and coiled-coil domain family 2 (467 aa)
     
 
  0.807
rbbp5
Retinoblastoma binding protein 5 (512 aa)
     
 
  0.730
klhl17
Kelch-like 17 (Drosophila) (591 aa)
     
 
  0.729
timm17a
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (166 aa)
     
   
  0.703
snrpe
Small nuclear ribonucleoprotein E; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins snrpb, snrpd1, snrpd2, snrpd3, snrpe, snrpf and snrpg that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3’-end processing. May indirectly play a role in hair development (By similarity) (92 aa)
       
 
  0.677
dcbld2
Discoidin, CUB and LCCL domain containing 2 (661 aa)
       
 
  0.654
lrrc32
Leucine-rich repeat-containing 32; Leucine rich repeat containing 32 (659 aa)
       
 
  0.641
poldip2
Polymerase (DNA-directed), delta interacting protein 2 (766 aa)
       
 
  0.621
meaf6
Chromatin modification-related protein MEAF6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in viv [...] (192 aa)
       
 
  0.619
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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