STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
il10Interleukin-10. (180 aa)    
Predicted Functional Partners:
il10rb
Interleukin 10 receptor, beta.
    
 0.992
il13
Interleukin 4/13A.
      
 0.992
crfb4
Cytokine receptor family member b4.
    
 0.990
tnfb
Tumor necrosis factor b (TNF superfamily, member 2).
   
  
 0.986
il1b
Interleukin-1.
   
  
 0.977
foxp3a
Forkhead box protein.
   
  
 0.958
il6
Interleukin 6 (interferon, beta 2).
      
 0.951
arg1
Arginase.
   
  
 0.947
tlr2
Toll-like receptor 2.
   
 
 0.943
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response.
      
 0.908
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.