STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q1L955_DANRESi:dkey-211g8.6; Belongs to the G-protein coupled receptor 1 family. (328 aa)    
Predicted Functional Partners:
pyya
Peptide YY-A; Belongs to the NPY family.
      
 0.640
gnaq
Guanine nucleotide-binding protein (G protein), q polypeptide.
    
 0.541
gna11b
Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).
    
 0.541
triob
Trio Rho guanine nucleotide exchange factor b.
    
  0.530
kalrnb
Kalirin RhoGEF kinase b.
    
  0.530
btk
Tyrosine-protein kinase.
    
  0.518
gna15.1
Guanine nucleotide-binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1.
    
  0.513
pik3r3b
Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma).
     
  0.499
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
     
  0.499
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
  0.499
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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