STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
myzapMyocardial zonula adherens protein. (584 aa)    
Predicted Functional Partners:
wu:fi04e12
Wu:fi04e12.
   
  
 0.741
dtnbp1a
Dysbindin-A; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neu [...]
      
 0.720
dcaf7
Ddb1 and cul4-associated factor 7.
      
 0.644
F1QKM6_DANRE
Si:dkeyp-69b9.3.
    
 
 0.618
kxd1
KxDL motif-containing protein 1; As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
   
   0.568
cmya5
Cardiomyopathy associated 5 like.
   
 
 0.565
tnnt2c
Troponin T1, skeletal, slow.
   
 
 0.524
gatd1
Glutamine amidotransferase-like class 1 domain-containing protein 1.
   
 
 0.524
tnnt3a
Troponin T type 3a (skeletal, fast).
   
 
 0.524
tnnt2d
Troponin T2d, cardiac.
   
 
 0.524
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]