STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nck1aNCK adaptor protein 1a. (332 aa)    
Predicted Functional Partners:
pak1
Non-specific serine/threonine protein kinase.
    
 0.841
pak2b
Non-specific serine/threonine protein kinase.
    
 0.838
pak2a
Non-specific serine/threonine protein kinase.
    
 0.838
fam217b
Family with sequence similarity 217 member B.
    
 
 0.809
pak4
Non-specific serine/threonine protein kinase.
    
 0.788
LOC100536197
Non-specific serine/threonine protein kinase.
    
 0.788
pak6b
Non-specific serine/threonine protein kinase.
    
 0.788
pak7
P21 protein (Cdc42/Rac)-activated kinase 7.
    
 0.788
manea
Mannosidase, endo-alpha.
   
  
 0.744
flj11011l
Probable ubiquitin-conjugating enzyme E2 W-B; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in degradation of misfolded chaperone substrate and DNA repair.
      
 0.742
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.