mylk3 protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mylk3

Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart. (716 aa)

Predicted Functional Partners:

calm2a

0.926

calml4a

0.916

prkceb

0.900

prkcea

0.900

calml4b

0.900

cmlc1

0.896

myl2b

0.817

mylpfa

0.791

myl4

0.783

myl7

0.780

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
calm2a	calml4a	ENSDARP00000010393	ENSDARP00000098981	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.	Calmodulin-like 4a.	0.907
calm2a	calml4b	ENSDARP00000010393	ENSDARP00000128395	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.	Calmodulin-like 4b.	0.904
calm2a	mylk3	ENSDARP00000010393	ENSDARP00000102547	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.	Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart.	0.926
calml4a	calm2a	ENSDARP00000098981	ENSDARP00000010393	Calmodulin-like 4a.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.	0.907
calml4a	calml4b	ENSDARP00000098981	ENSDARP00000128395	Calmodulin-like 4a.	Calmodulin-like 4b.	0.902
calml4a	mylk3	ENSDARP00000098981	ENSDARP00000102547	Calmodulin-like 4a.	Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart.	0.916
calml4b	calm2a	ENSDARP00000128395	ENSDARP00000010393	Calmodulin-like 4b.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.	0.904
calml4b	calml4a	ENSDARP00000128395	ENSDARP00000098981	Calmodulin-like 4b.	Calmodulin-like 4a.	0.902
calml4b	mylk3	ENSDARP00000128395	ENSDARP00000102547	Calmodulin-like 4b.	Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart.	0.900
cmlc1	myl2b	ENSDARP00000048394	ENSDARP00000116241	Cardiac myosin light chain-1.	Myosin, light polypeptide 2, regulatory, cardiac, slow.	0.498
cmlc1	myl4	ENSDARP00000048394	ENSDARP00000153187	Cardiac myosin light chain-1.	Myosin, light chain 4, alkali; atrial, embryonic.	0.566
cmlc1	myl7	ENSDARP00000048394	ENSDARP00000040012	Cardiac myosin light chain-1.	Myosin, light polypeptide 7, regulatory.	0.984
cmlc1	mylk3	ENSDARP00000048394	ENSDARP00000102547	Cardiac myosin light chain-1.	Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart.	0.896
cmlc1	mylpfa	ENSDARP00000048394	ENSDARP00000069948	Cardiac myosin light chain-1.	Myosin light chain, phosphorylatable, fast skeletal muscle a.	0.516
myl2b	cmlc1	ENSDARP00000116241	ENSDARP00000048394	Myosin, light polypeptide 2, regulatory, cardiac, slow.	Cardiac myosin light chain-1.	0.498
myl2b	myl4	ENSDARP00000116241	ENSDARP00000153187	Myosin, light polypeptide 2, regulatory, cardiac, slow.	Myosin, light chain 4, alkali; atrial, embryonic.	0.692
myl2b	mylk3	ENSDARP00000116241	ENSDARP00000102547	Myosin, light polypeptide 2, regulatory, cardiac, slow.	Myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro (By similarity). Increases cardiomyocyte contractility (By similarity). Required for sarcomere formation in the developing heart.	0.817
myl4	cmlc1	ENSDARP00000153187	ENSDARP00000048394	Myosin, light chain 4, alkali; atrial, embryonic.	Cardiac myosin light chain-1.	0.566
myl4	myl2b	ENSDARP00000153187	ENSDARP00000116241	Myosin, light chain 4, alkali; atrial, embryonic.	Myosin, light polypeptide 2, regulatory, cardiac, slow.	0.692
myl4	myl7	ENSDARP00000153187	ENSDARP00000040012	Myosin, light chain 4, alkali; atrial, embryonic.	Myosin, light polypeptide 7, regulatory.	0.696

page 1 of 3

Server load: medium (44%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2023

Credits

Access

Info

About