STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eloalElongin A,-like. (586 aa)    
Predicted Functional Partners:
eloca
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.967
elocb
Elongin C paralog b; Belongs to the SKP1 family.
    
 0.967
leo1
RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). PAF1C seems to be required for multiple steps in cardiac formation. Involved in heart development and required for differentiation of the atrioventricular boundary. Required for neural crest cell development.
    
 0.879
rpl23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
    
 
 0.814
rpl18
Ribosomal protein L18.
   
   0.805
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
    
 
 0.795
rpl3
Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
    
   0.794
rpl35
60S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family.
    
   0.794
rpl18a
60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.
    
   0.794
rpl30
Ribosomal protein L30.
    
   0.794
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.