STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cgnl1Cingulin-like 1. (1307 aa)    
Predicted Functional Partners:
arhgef2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
   
 
 0.943
arhgef1a
Rho guanine nucleotide exchange factor (GEF) 1a.
     
 0.942
tjp1a
Tight junction protein 1a; Belongs to the MAGUK family.
    
 0.935
nectin4b
Nectin cell adhesion molecule 4b.
      
 0.644
pdzd11
PDZ domain-containing protein 11.
      
 0.620
plekha7b
Pleckstrin homology domain-containing, family A member 7b.
      
 0.598
LOC100535428
NACHT domain-containing protein.
   
 
 0.586
rhbdl2
Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
      
 0.586
trappc1
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
    
 
 0.585
trappc8
Trafficking protein particle complex 8.
    
 
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.