node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
X1WHF1_DANRE | glyr1 | ENSDARP00000129663 | ENSDARP00000137468 | Histone H2B; Belongs to the histone H2B family. | Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. | 0.532 |
X1WHF1_DANRE | h1-10 | ENSDARP00000129663 | ENSDARP00000070677 | Histone H2B; Belongs to the histone H2B family. | H1 histone family, member X. | 0.411 |
X1WHF1_DANRE | hist2h2l | ENSDARP00000129663 | ENSDARP00000055912 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.405 |
X1WHF1_DANRE | macroh2a2 | ENSDARP00000129663 | ENSDARP00000105230 | Histone H2B; Belongs to the histone H2B family. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.732 |
X1WHF1_DANRE | parp1 | ENSDARP00000129663 | ENSDARP00000008364 | Histone H2B; Belongs to the histone H2B family. | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. | 0.403 |
glyr1 | X1WHF1_DANRE | ENSDARP00000137468 | ENSDARP00000129663 | Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. | Histone H2B; Belongs to the histone H2B family. | 0.532 |
glyr1 | hist2h2l | ENSDARP00000137468 | ENSDARP00000055912 | Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.532 |
glyr1 | macroh2a2 | ENSDARP00000137468 | ENSDARP00000105230 | Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.703 |
h1-10 | X1WHF1_DANRE | ENSDARP00000070677 | ENSDARP00000129663 | H1 histone family, member X. | Histone H2B; Belongs to the histone H2B family. | 0.411 |
h1-10 | hist2h2l | ENSDARP00000070677 | ENSDARP00000055912 | H1 histone family, member X. | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.516 |
h1-10 | histh1l | ENSDARP00000070677 | ENSDARP00000109050 | H1 histone family, member X. | Histone H1-like. | 0.412 |
h1-10 | macroh2a2 | ENSDARP00000070677 | ENSDARP00000105230 | H1 histone family, member X. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.676 |
hist2h2l | X1WHF1_DANRE | ENSDARP00000055912 | ENSDARP00000129663 | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B; Belongs to the histone H2B family. | 0.405 |
hist2h2l | glyr1 | ENSDARP00000055912 | ENSDARP00000137468 | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. | 0.532 |
hist2h2l | h1-10 | ENSDARP00000055912 | ENSDARP00000070677 | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H1 histone family, member X. | 0.516 |
hist2h2l | macroh2a2 | ENSDARP00000055912 | ENSDARP00000105230 | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.767 |
hist2h2l | parp1 | ENSDARP00000055912 | ENSDARP00000008364 | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. | 0.403 |
histh1l | h1-10 | ENSDARP00000109050 | ENSDARP00000070677 | Histone H1-like. | H1 histone family, member X. | 0.412 |
histh1l | macroh2a2 | ENSDARP00000109050 | ENSDARP00000105230 | Histone H1-like. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.665 |
macroh2a2 | X1WHF1_DANRE | ENSDARP00000105230 | ENSDARP00000129663 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | Histone H2B; Belongs to the histone H2B family. | 0.732 |