node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
lamtor1 | lamtor2 | ENSDARP00000103059 | ENSDARP00000058324 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor1 | lamtor3 | ENSDARP00000103059 | ENSDARP00000116826 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor1 | lamtor4 | ENSDARP00000103059 | ENSDARP00000115287 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ragulator complex protein LAMTOR4; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | 0.999 |
lamtor1 | lamtor5 | ENSDARP00000103059 | ENSDARP00000106008 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. | 0.999 |
lamtor1 | rptor | ENSDARP00000103059 | ENSDARP00000132117 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Regulatory-associated protein of MTOR, complex 1. | 0.994 |
lamtor1 | rraga | ENSDARP00000103059 | ENSDARP00000151097 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding A. | 0.959 |
lamtor1 | rragca | ENSDARP00000103059 | ENSDARP00000092718 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding Ca. | 0.976 |
lamtor1 | rragcb | ENSDARP00000103059 | ENSDARP00000142003 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding Cb. | 0.976 |
lamtor1 | rragd | ENSDARP00000103059 | ENSDARP00000015934 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Ras-related GTP-binding D. | 0.976 |
lamtor1 | slc38a9 | ENSDARP00000103059 | ENSDARP00000041067 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.999 |
lamtor2 | lamtor1 | ENSDARP00000058324 | ENSDARP00000103059 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. | 0.999 |
lamtor2 | lamtor3 | ENSDARP00000058324 | ENSDARP00000116826 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.999 |
lamtor2 | lamtor4 | ENSDARP00000058324 | ENSDARP00000115287 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ragulator complex protein LAMTOR4; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | 0.999 |
lamtor2 | lamtor5 | ENSDARP00000058324 | ENSDARP00000106008 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. | 0.999 |
lamtor2 | rptor | ENSDARP00000058324 | ENSDARP00000132117 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Regulatory-associated protein of MTOR, complex 1. | 0.944 |
lamtor2 | rraga | ENSDARP00000058324 | ENSDARP00000151097 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ras-related GTP-binding A. | 0.971 |
lamtor2 | rragca | ENSDARP00000058324 | ENSDARP00000092718 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ras-related GTP-binding Ca. | 0.978 |
lamtor2 | rragcb | ENSDARP00000058324 | ENSDARP00000142003 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ras-related GTP-binding Cb. | 0.978 |
lamtor2 | rragd | ENSDARP00000058324 | ENSDARP00000015934 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Ras-related GTP-binding D. | 0.978 |
lamtor2 | slc38a9 | ENSDARP00000058324 | ENSDARP00000041067 | Ragulator complex protein LAMTOR2; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.999 |