STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mxaInterferon-induced GTP-binding protein MxA; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (632 aa)    
Predicted Functional Partners:
rsad2
Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon; Belongs to the radical SAM superfamily. RSAD2 family.
   
  
 0.953
ifnphi1
Interferon phi 1.
   
  
 0.841
ifnphi3
Interferon phi 3.
      
 0.831
pkz
Protein kinase-containing Z-DNA-binding domains.
   
 
 0.809
ifnphi2
Type I interferon 2.
      
 0.805
irf7
Interferon regulatory factor 7.
   
  
 0.785
irf3
Interferon regulatory factor 3.
   
  
 0.742
usp18
Ubiquitin-specific peptidase 18; Belongs to the peptidase C19 family.
   
 
 0.738
eif2ak2
Eukaryotic translation initiation factor 2-alpha kinase 2.
   
 
 0.734
tlr3
Toll-like receptor 3; Belongs to the Toll-like receptor family.
   
 
 0.698
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.