node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gcgb | ins | ENSDARP00000112837 | ENSDARP00000051221 | Glucagon b. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.997 |
gcgb | insb | ENSDARP00000112837 | ENSDARP00000115146 | Glucagon b. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.993 |
gcgb | neurog3 | ENSDARP00000112837 | ENSDARP00000106489 | Glucagon b. | Neurog3 protein. | 0.860 |
gcgb | nkx2.2a | ENSDARP00000112837 | ENSDARP00000153588 | Glucagon b. | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). | 0.661 |
gcgb | nkx6.1 | ENSDARP00000112837 | ENSDARP00000035373 | Glucagon b. | NK6 homeobox 1. | 0.838 |
gcgb | onecut1 | ENSDARP00000112837 | ENSDARP00000026697 | Glucagon b. | One cut domain family member. | 0.452 |
gcgb | pax4 | ENSDARP00000112837 | ENSDARP00000013792 | Glucagon b. | Paired box 4. | 0.861 |
gcgb | pax6a | ENSDARP00000112837 | ENSDARP00000135767 | Glucagon b. | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.570 |
gcgb | pdx1 | ENSDARP00000112837 | ENSDARP00000017531 | Glucagon b. | Pancreatic and duodenal homeobox 1. | 0.855 |
gcgb | rfx6 | ENSDARP00000112837 | ENSDARP00000116051 | Glucagon b. | DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Belongs to the RFX family. | 0.492 |
ins | gcgb | ENSDARP00000051221 | ENSDARP00000112837 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Glucagon b. | 0.997 |
ins | insb | ENSDARP00000051221 | ENSDARP00000115146 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.905 |
ins | neurog3 | ENSDARP00000051221 | ENSDARP00000106489 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Neurog3 protein. | 0.864 |
ins | nkx2.2a | ENSDARP00000051221 | ENSDARP00000153588 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Homeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). | 0.674 |
ins | nkx6.1 | ENSDARP00000051221 | ENSDARP00000035373 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | NK6 homeobox 1. | 0.834 |
ins | onecut1 | ENSDARP00000051221 | ENSDARP00000026697 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | One cut domain family member. | 0.550 |
ins | pax4 | ENSDARP00000051221 | ENSDARP00000013792 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Paired box 4. | 0.843 |
ins | pax6a | ENSDARP00000051221 | ENSDARP00000135767 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.736 |
ins | pdx1 | ENSDARP00000051221 | ENSDARP00000017531 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Pancreatic and duodenal homeobox 1. | 0.881 |
ins | rfx6 | ENSDARP00000051221 | ENSDARP00000116051 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | DNA-binding protein RFX6; Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Belongs to the RFX family. | 0.631 |