STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
armc9LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling (By similarity). Involved in ciliogenesis. (544 aa)    
Predicted Functional Partners:
F1R3W2_DANRE
Si:dkey-161j23.5.
      
 0.837
gid8a
Glucose-induced degradation protein 8-A homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (By similarity). Required for normal Wnt signaling and normal dorsoventral patterning during embryogenesis. Belongs to the GID8 family.
      
 0.745
gid8b
Glucose-induced degradation protein 8-B homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (By similarity). Required for normal Wnt signaling and normal dorsoventral patterning during embryogenesis.
      
 0.745
cspp1
Centrosome and spindle pole-associated protein 1a.
      
 0.744
rpusd1
RNA pseudouridylate synthase domain-containing protein 1; Belongs to the pseudouridine synthase RluA family.
      
 0.743
ttc23
Tetratricopeptide repeat domain 23.
      
 0.724
ttll10
Tubulin tyrosine ligase-like family, member 10.
      
 0.707
txndc15
Interferon regulatory factor 1b.
      
 0.697
ARMC6
Armadillo repeat containing 6.
    
 
 0.667
armc3
Armadillo repeat-containing 3.
      
 0.645
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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