ric8a protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ric8a

Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity). (550 aa)

Predicted Functional Partners:

gnaq

0.822

gna11a

0.787

aldh18a1

0.701

gna11b

0.628

gna14a

0.628

rabif

0.626

ncs1a

0.613

gnat1

0.599

gnat2

0.595

gna12a

0.571

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aldh18a1	ric8a	ENSDARP00000137162	ENSDARP00000044737	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).	0.701
gna11a	gna11b	ENSDARP00000123118	ENSDARP00000044410	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	0.555
gna11a	gna12a	ENSDARP00000123118	ENSDARP00000050331	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.598
gna11a	gna14a	ENSDARP00000123118	ENSDARP00000122726	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein), alpha 14a.	0.545
gna11a	gnaq	ENSDARP00000123118	ENSDARP00000020119	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein), q polypeptide.	0.552
gna11a	gnat1	ENSDARP00000123118	ENSDARP00000064895	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1.	0.572
gna11a	gnat2	ENSDARP00000123118	ENSDARP00000062362	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 2.	0.575
gna11a	ric8a	ENSDARP00000123118	ENSDARP00000044737	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).	0.787
gna11b	gna11a	ENSDARP00000044410	ENSDARP00000123118	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	0.555
gna11b	gna12a	ENSDARP00000044410	ENSDARP00000050331	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein) alpha 12a.	0.583
gna11b	gna14a	ENSDARP00000044410	ENSDARP00000122726	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein), alpha 14a.	0.545
gna11b	gnaq	ENSDARP00000044410	ENSDARP00000020119	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein), q polypeptide.	0.901
gna11b	gnat1	ENSDARP00000044410	ENSDARP00000064895	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1.	0.568
gna11b	gnat2	ENSDARP00000044410	ENSDARP00000062362	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 2.	0.569
gna11b	ric8a	ENSDARP00000044410	ENSDARP00000044737	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).	0.628
gna12a	gna11a	ENSDARP00000050331	ENSDARP00000123118	Guanine nucleotide-binding protein (G protein) alpha 12a.	Guanine nucleotide-binding protein (G protein), alpha 11a (Gq class).	0.598
gna12a	gna11b	ENSDARP00000050331	ENSDARP00000044410	Guanine nucleotide-binding protein (G protein) alpha 12a.	Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).	0.583
gna12a	gna14a	ENSDARP00000050331	ENSDARP00000122726	Guanine nucleotide-binding protein (G protein) alpha 12a.	Guanine nucleotide-binding protein (G protein), alpha 14a.	0.581
gna12a	gnaq	ENSDARP00000050331	ENSDARP00000020119	Guanine nucleotide-binding protein (G protein) alpha 12a.	Guanine nucleotide-binding protein (G protein), q polypeptide.	0.717
gna12a	gnat1	ENSDARP00000050331	ENSDARP00000064895	Guanine nucleotide-binding protein (G protein) alpha 12a.	Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1.	0.590

page 1 of 4

Server load: medium (80%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2023

Credits

Access

Info

About