STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adprhADP-ribosylarginine hydrolase. (353 aa)    
Predicted Functional Partners:
paqr4b
Progestin and adipoQ receptor family member IVb.
      
 0.994
sult1st6
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.957
ppp1cab
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.874
pelo
Protein pelota homolog; Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
   
  
 0.871
mid1ip1a
Mid1-interacting protein 1A; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family.
      
 0.856
mto1
Mitochondrial tRNA translation optimization 1.
   
  
 0.789
atp2a1l
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
  
 0.774
ube2f
NEDD8-conjugating enzyme UBE2F; Accepts the ubiquitin-like protein NEDD8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase rbx2, but not rbx1, suggests that the rbx2-ube2f complex neddylates specific target proteins, such as cul5; Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
    
 
 0.583
UBE2M
Si:ch1073-205c8.3; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.583
cacul1
CDK2-associated cullin domain 1; Belongs to the cullin family.
   
 
 0.470
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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