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dpysl3 protein (Danio rerio) - STRING interaction network
"dpysl3" - Dihydropyrimidinase-related protein 3 in Danio rerio
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dpysl3Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family (679 aa)    
Predicted Functional Partners:
dpysl2b
Dihydropyrimidinase-like 2b (536 aa)
   
0.996
crmp1
Collapsin response mediator protein 1 (674 aa)
   
0.977
cdk5
Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily (292 aa)
         
  0.974
plxna4
Plexin-A4; Involved in the development of primary sensory neurons especially in branching of the peripheral axons. Interacts with the SLIT2 signaling specifically to promote axonal branching of Rohon-Beard neurons and the trigeminal sensory ganglion neurons (1903 aa)
     
 
  0.962
nrp1a
Neuropilin-1a; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. Regulates angiogenesis through a VEGF-dependent pathway (926 aa)
     
 
  0.944
PLXNA2
Plexin A2 (1850 aa)
     
 
  0.943
sema3ab
Semaphorin-3ab; Might normally influence the midsegmental pathway choice of the ventrally extending motor axons by contributing to a repulsive domain in the posterior somite (778 aa)
     
 
  0.941
dpysl4
Dihydropyrimidinase-like 4 (574 aa)
   
0.936
ENSDARG00000052468
Si-dkeyp-80c12.7; Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily (419 aa)
     
  0.932
gsk3b
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily (421 aa)
     
  0.931
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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