STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrg2bNeuregulin 2b. (705 aa)    
Predicted Functional Partners:
erbb3a
Erb-b2 receptor tyrosine kinase 3a.
    
 0.962
erbb4a
Receptor protein-tyrosine kinase.
    
 0.960
erbb3b
Erb-b2 receptor tyrosine kinase 3b.
    
 0.955
ENSDARP00000086547
Receptor protein-tyrosine kinase.
    
 0.940
erbb4b
Receptor protein-tyrosine kinase.
    
 0.940
nrg2a
Zgc:162973 protein.
  
  
0.904
LOC101884653
Ribonuclease/angiogenin inhibitor 1.
   
 
 0.845
nrg1
Neuregulin 1.
     
0.829
erbb2
Receptor protein-tyrosine kinase.
    
 0.746
LOC100002059
ADAM metallopeptidase with thrombospondin type 1 motif, 15b.
      
 0.744
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (54%) [HD]