node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acta1b | ezra | ENSDARP00000058628 | ENSDARP00000108896 | Actin alpha 1, skeletal muscle b. | Ezrl protein. | 0.622 |
acta1b | podxl | ENSDARP00000058628 | ENSDARP00000093077 | Actin alpha 1, skeletal muscle b. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. | 0.631 |
acta1b | slc9a1b | ENSDARP00000058628 | ENSDARP00000088401 | Actin alpha 1, skeletal muscle b. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.554 |
acta1b | slc9a3r1a | ENSDARP00000058628 | ENSDARP00000000069 | Actin alpha 1, skeletal muscle b. | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. | 0.561 |
actb1 | actb2 | ENSDARP00000054986 | ENSDARP00000122263 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.908 |
actb1 | ezra | ENSDARP00000054986 | ENSDARP00000108896 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Ezrl protein. | 0.914 |
actb2 | actb1 | ENSDARP00000122263 | ENSDARP00000054986 | Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.908 |
actb2 | ezra | ENSDARP00000122263 | ENSDARP00000108896 | Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Ezrl protein. | 0.914 |
elmo1 | ezra | ENSDARP00000132398 | ENSDARP00000108896 | Engulfment and Cell motility 1 (Ced-12 homolog, C. elegans). | Ezrl protein. | 0.607 |
ezra | acta1b | ENSDARP00000108896 | ENSDARP00000058628 | Ezrl protein. | Actin alpha 1, skeletal muscle b. | 0.622 |
ezra | actb1 | ENSDARP00000108896 | ENSDARP00000054986 | Ezrl protein. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.914 |
ezra | actb2 | ENSDARP00000108896 | ENSDARP00000122263 | Ezrl protein. | Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.914 |
ezra | elmo1 | ENSDARP00000108896 | ENSDARP00000132398 | Ezrl protein. | Engulfment and Cell motility 1 (Ced-12 homolog, C. elegans). | 0.607 |
ezra | podxl | ENSDARP00000108896 | ENSDARP00000093077 | Ezrl protein. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. | 0.580 |
ezra | prkcea | ENSDARP00000108896 | ENSDARP00000096385 | Ezrl protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.902 |
ezra | prkceb | ENSDARP00000108896 | ENSDARP00000045085 | Ezrl protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.903 |
ezra | slc9a1b | ENSDARP00000108896 | ENSDARP00000088401 | Ezrl protein. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.911 |
ezra | slc9a3r1a | ENSDARP00000108896 | ENSDARP00000000069 | Ezrl protein. | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. | 0.961 |
ezra | sytl2a | ENSDARP00000108896 | ENSDARP00000083406 | Ezrl protein. | Synaptotagmin-like 2a. | 0.591 |
podxl | acta1b | ENSDARP00000093077 | ENSDARP00000058628 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. | Actin alpha 1, skeletal muscle b. | 0.631 |