STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdc42se1CDC42 small effector protein 1; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly; Belongs to the CDC42SE/SPEC family. (75 aa)    
Predicted Functional Partners:
arhgef19
Rho guanine nucleotide exchange factor (GEF) 19.
      
 0.831
en2a
Homeobox protein engrailed-2a.
      
 0.803
grhl2b
Grainyhead-like transcription factor 2b.
   
  
 0.692
tgm1
Transglutaminase 1, K polypeptide.
      
 0.664
pnpla4
Patatin-like phospholipase domain-containing 4.
   
  
 0.634
cdc42ep4b
CDC42 effector protein (Rho GTPase-binding) 4b.
   
  
 0.626
grhl3
Grainyhead-like transcription factor 3.
      
 0.583
tmed2
Transmembrane p24-trafficking protein 2.
      
 0.565
flii
FLII actin-remodeling protein.
      
 0.560
cdc42
Cell division cycle 42.
    
 
 0.524
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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