node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arfgef2 | dchs1b | ENSDARP00000101022 | ENSDARP00000109139 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). | Dachsous cadherin-related 1b. | 0.802 |
cdhr5b | ctnna1 | ENSDARP00000135376 | ENSDARP00000132933 | Cadherin-related family member 5b. | Catenin (cadherin-associated protein), alpha 1. | 0.710 |
cdhr5b | ctnna2 | ENSDARP00000135376 | ENSDARP00000092080 | Cadherin-related family member 5b. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | 0.710 |
cdhr5b | ctnnb1 | ENSDARP00000135376 | ENSDARP00000139205 | Cadherin-related family member 5b. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.711 |
cdhr5b | ctnnb2 | ENSDARP00000135376 | ENSDARP00000076115 | Cadherin-related family member 5b. | Catenin, beta 2. | 0.711 |
cdhr5b | dchs1b | ENSDARP00000135376 | ENSDARP00000109139 | Cadherin-related family member 5b. | Dachsous cadherin-related 1b. | 0.731 |
cdhr5b | jupa | ENSDARP00000135376 | ENSDARP00000026915 | Cadherin-related family member 5b. | Junction plakoglobin a. | 0.707 |
ctnna1 | cdhr5b | ENSDARP00000132933 | ENSDARP00000135376 | Catenin (cadherin-associated protein), alpha 1. | Cadherin-related family member 5b. | 0.710 |
ctnna1 | ctnna2 | ENSDARP00000132933 | ENSDARP00000092080 | Catenin (cadherin-associated protein), alpha 1. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | 0.901 |
ctnna1 | ctnnb1 | ENSDARP00000132933 | ENSDARP00000139205 | Catenin (cadherin-associated protein), alpha 1. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.978 |
ctnna1 | ctnnb2 | ENSDARP00000132933 | ENSDARP00000076115 | Catenin (cadherin-associated protein), alpha 1. | Catenin, beta 2. | 0.976 |
ctnna1 | dchs1b | ENSDARP00000132933 | ENSDARP00000109139 | Catenin (cadherin-associated protein), alpha 1. | Dachsous cadherin-related 1b. | 0.759 |
ctnna1 | jupa | ENSDARP00000132933 | ENSDARP00000026915 | Catenin (cadherin-associated protein), alpha 1. | Junction plakoglobin a. | 0.945 |
ctnna2 | cdhr5b | ENSDARP00000092080 | ENSDARP00000135376 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Cadherin-related family member 5b. | 0.710 |
ctnna2 | ctnna1 | ENSDARP00000092080 | ENSDARP00000132933 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Catenin (cadherin-associated protein), alpha 1. | 0.901 |
ctnna2 | ctnnb1 | ENSDARP00000092080 | ENSDARP00000139205 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.977 |
ctnna2 | ctnnb2 | ENSDARP00000092080 | ENSDARP00000076115 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Catenin, beta 2. | 0.968 |
ctnna2 | dchs1b | ENSDARP00000092080 | ENSDARP00000109139 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Dachsous cadherin-related 1b. | 0.775 |
ctnna2 | jupa | ENSDARP00000092080 | ENSDARP00000026915 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. | Junction plakoglobin a. | 0.874 |
ctnnb1 | cdhr5b | ENSDARP00000139205 | ENSDARP00000135376 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Cadherin-related family member 5b. | 0.711 |