STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpf3Zinc finger protein DPF3; Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4. In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). Plays an essential role in heart and skeletal [...] (391 aa)    
Predicted Functional Partners:
smarce1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily e, member 1.
   
 0.906
actl6b
Actin-like 6B; Belongs to the actin family.
   
 0.892
smarcc2
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 2.
   
 0.888
actl6a
Actin-like 6A; Belongs to the actin family.
   
 0.854
smarcd1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 1.
   
 0.851
arid1b
AT-rich interactive domain 1B (SWI1-like).
   
 0.833
smarcc1a
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily c, member 1a.
   
 0.806
smarca4a
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 4a.
    
 0.792
smarcb1a
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A; Involved in chromatin-remodeling. Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity).
   
 0.784
smarcb1b
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.
   
 0.784
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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