STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foxp1bForkhead box protein P1-B; Transcriptional repressor. (659 aa)    
Predicted Functional Partners:
cntnap2b
Contactin-associated protein 2b.
      
 0.735
hoxc9a
Homeobox protein Hox-C9a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    
 
 0.727
LHX3
LIM/homeobox protein Lhx3.
    
 
 0.690
zgc:113054
Zgc:113054.
   
  
 0.667
isl1
Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity).
      
 0.655
SHKBP1
SH3KBP1 binding protein 1.
      
 0.644
MDFIC
Si:ch211-262n1.4.
      
 0.574
olig2
Oligodendrocyte lineage transcription factor 2.
   
  
 0.573
lhx1a
LIM/homeobox protein Lhx1; Seems to play a role in dorsal axis formation.
      
 0.556
adnpb
Activity-dependent neuroprotector homeobox b.
      
 0.542
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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