node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ak9 | cmpk2 | ENSDARP00000118427 | ENSDARP00000113379 | Adenylate kinase 9. | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | 0.972 |
ak9 | ctps1a | ENSDARP00000118427 | ENSDARP00000121703 | Adenylate kinase 9. | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | 0.948 |
ak9 | ctps1b | ENSDARP00000118427 | ENSDARP00000139667 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.948 |
ak9 | dtymk | ENSDARP00000118427 | ENSDARP00000068373 | Adenylate kinase 9. | Deoxythymidylate kinase (thymidylate kinase). | 0.972 |
ak9 | guk1b | ENSDARP00000118427 | ENSDARP00000023640 | Adenylate kinase 9. | Guanylate kinase 1b. | 0.950 |
ak9 | hddc3 | ENSDARP00000118427 | ENSDARP00000033279 | Adenylate kinase 9. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response. | 0.942 |
ak9 | itpa | ENSDARP00000118427 | ENSDARP00000074674 | Adenylate kinase 9. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.947 |
ak9 | nme2a | ENSDARP00000118427 | ENSDARP00000064338 | Adenylate kinase 9. | Nucleoside diphosphate kinase. | 0.950 |
ak9 | ntpcr | ENSDARP00000118427 | ENSDARP00000033890 | Adenylate kinase 9. | Nucleoside-triphosphatase, cancer-related. | 0.916 |
ak9 | rrm1 | ENSDARP00000118427 | ENSDARP00000010800 | Adenylate kinase 9. | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.960 |
cmpk2 | ak9 | ENSDARP00000113379 | ENSDARP00000118427 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | Adenylate kinase 9. | 0.972 |
cmpk2 | dtymk | ENSDARP00000113379 | ENSDARP00000068373 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | Deoxythymidylate kinase (thymidylate kinase). | 0.574 |
cmpk2 | itpa | ENSDARP00000113379 | ENSDARP00000074674 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.590 |
cmpk2 | nme2a | ENSDARP00000113379 | ENSDARP00000064338 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | Nucleoside diphosphate kinase. | 0.946 |
cmpk2 | rrm1 | ENSDARP00000113379 | ENSDARP00000010800 | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.973 |
ctps1a | ak9 | ENSDARP00000121703 | ENSDARP00000118427 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Adenylate kinase 9. | 0.948 |
ctps1a | ctps1b | ENSDARP00000121703 | ENSDARP00000139667 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.901 |
ctps1a | dtymk | ENSDARP00000121703 | ENSDARP00000068373 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Deoxythymidylate kinase (thymidylate kinase). | 0.780 |
ctps1a | itpa | ENSDARP00000121703 | ENSDARP00000074674 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.858 |
ctps1a | nme2a | ENSDARP00000121703 | ENSDARP00000064338 | CTP synthase 1; This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. | Nucleoside diphosphate kinase. | 0.946 |