node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acvr1l | bmp2b | ENSDARP00000003221 | ENSDARP00000107417 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 2b. | 0.981 |
acvr1l | bmp4 | ENSDARP00000003221 | ENSDARP00000069635 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 4. | 0.985 |
acvr1l | bmp5 | ENSDARP00000003221 | ENSDARP00000134612 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 5. | 0.981 |
acvr1l | bmp6 | ENSDARP00000003221 | ENSDARP00000022649 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 6. | 0.998 |
acvr1l | bmp7a | ENSDARP00000003221 | ENSDARP00000017352 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Bone morphogenetic protein 7a. | 0.995 |
acvr1l | smad1 | ENSDARP00000003221 | ENSDARP00000030150 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog 1; Involved in ventralization. May mediate Bmp2b signaling during embryonic dorsal-ventral pattern formation, and may itself be a transcriptional target for Smad5-mediated Bmp2b signaling. Belongs to the dwarfin/SMAD family. | 0.980 |
acvr1l | smad2 | ENSDARP00000003221 | ENSDARP00000106756 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. | 0.985 |
acvr1l | smad3a | ENSDARP00000003221 | ENSDARP00000045373 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.971 |
acvr1l | smad5 | ENSDARP00000003221 | ENSDARP00000054174 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog 5; Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation. Belongs to the dwarfin/SMAD family. | 0.993 |
acvr1l | smad9 | ENSDARP00000003221 | ENSDARP00000131023 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.988 |
bmp2b | acvr1l | ENSDARP00000107417 | ENSDARP00000003221 | Bone morphogenetic protein 2b. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.981 |
bmp2b | bmp4 | ENSDARP00000107417 | ENSDARP00000069635 | Bone morphogenetic protein 2b. | Bone morphogenetic protein 4. | 0.462 |
bmp2b | bmp5 | ENSDARP00000107417 | ENSDARP00000134612 | Bone morphogenetic protein 2b. | Bone morphogenetic protein 5. | 0.439 |
bmp2b | bmp6 | ENSDARP00000107417 | ENSDARP00000022649 | Bone morphogenetic protein 2b. | Bone morphogenetic protein 6. | 0.441 |
bmp2b | bmp7a | ENSDARP00000107417 | ENSDARP00000017352 | Bone morphogenetic protein 2b. | Bone morphogenetic protein 7a. | 0.801 |
bmp2b | smad1 | ENSDARP00000107417 | ENSDARP00000030150 | Bone morphogenetic protein 2b. | Mothers against decapentaplegic homolog 1; Involved in ventralization. May mediate Bmp2b signaling during embryonic dorsal-ventral pattern formation, and may itself be a transcriptional target for Smad5-mediated Bmp2b signaling. Belongs to the dwarfin/SMAD family. | 0.947 |
bmp2b | smad2 | ENSDARP00000107417 | ENSDARP00000106756 | Bone morphogenetic protein 2b. | Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. | 0.646 |
bmp2b | smad3a | ENSDARP00000107417 | ENSDARP00000045373 | Bone morphogenetic protein 2b. | Mothers against decapentaplegic homolog. | 0.526 |
bmp2b | smad5 | ENSDARP00000107417 | ENSDARP00000054174 | Bone morphogenetic protein 2b. | Mothers against decapentaplegic homolog 5; Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation. Belongs to the dwarfin/SMAD family. | 0.945 |
bmp2b | smad9 | ENSDARP00000107417 | ENSDARP00000131023 | Bone morphogenetic protein 2b. | Mothers against decapentaplegic homolog. | 0.822 |