node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bdnf | cdk5 | ENSDARP00000010990 | ENSDARP00000073666 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. | 0.634 |
bdnf | egf | ENSDARP00000010990 | ENSDARP00000069126 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Epidermal growth factor. | 0.744 |
bdnf | igf2a | ENSDARP00000010990 | ENSDARP00000016954 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Insulin-like growth factor 2a. | 0.673 |
bdnf | nes | ENSDARP00000010990 | ENSDARP00000112046 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | 0.561 |
bdnf | pou5f3 | ENSDARP00000010990 | ENSDARP00000065816 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...] | 0.505 |
bdnf | pvalb6 | ENSDARP00000010990 | ENSDARP00000119857 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | Parvalbumin isoform 4b; Belongs to the parvalbumin family. | 0.694 |
bdnf | rbfox3a | ENSDARP00000010990 | ENSDARP00000144068 | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. | 0.470 |
cdk5 | bdnf | ENSDARP00000073666 | ENSDARP00000010990 | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.634 |
cdk5 | nes | ENSDARP00000073666 | ENSDARP00000112046 | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | 0.560 |
egf | bdnf | ENSDARP00000069126 | ENSDARP00000010990 | Epidermal growth factor. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.744 |
egf | igf2a | ENSDARP00000069126 | ENSDARP00000016954 | Epidermal growth factor. | Insulin-like growth factor 2a. | 0.661 |
egf | nes | ENSDARP00000069126 | ENSDARP00000112046 | Epidermal growth factor. | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | 0.559 |
egf | pou5f3 | ENSDARP00000069126 | ENSDARP00000065816 | Epidermal growth factor. | POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...] | 0.659 |
egf | vim | ENSDARP00000069126 | ENSDARP00000016261 | Epidermal growth factor. | Vimentin; Belongs to the intermediate filament family. | 0.439 |
igf2a | bdnf | ENSDARP00000016954 | ENSDARP00000010990 | Insulin-like growth factor 2a. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.673 |
igf2a | egf | ENSDARP00000016954 | ENSDARP00000069126 | Insulin-like growth factor 2a. | Epidermal growth factor. | 0.661 |
igf2a | nes | ENSDARP00000016954 | ENSDARP00000112046 | Insulin-like growth factor 2a. | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | 0.480 |
nes | bdnf | ENSDARP00000112046 | ENSDARP00000010990 | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. | 0.561 |
nes | cdk5 | ENSDARP00000112046 | ENSDARP00000073666 | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. | 0.560 |
nes | egf | ENSDARP00000112046 | ENSDARP00000069126 | Nestin; Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Required for brain and eye development. | Epidermal growth factor. | 0.559 |