node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adss2 | asns | ENSDARP00000028137 | ENSDARP00000107713 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.934 |
adss2 | aspa | ENSDARP00000028137 | ENSDARP00000068606 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.900 |
adss2 | asrgl1 | ENSDARP00000028137 | ENSDARP00000033788 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Isoaspartyl peptidase/L-asparaginase alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. | 0.905 |
adss2 | cad | ENSDARP00000028137 | ENSDARP00000127377 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.956 |
adss2 | got1 | ENSDARP00000028137 | ENSDARP00000129948 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.928 |
adss2 | got1l1 | ENSDARP00000028137 | ENSDARP00000070190 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamic-oxaloacetic transaminase 1-like 1. | 0.926 |
adss2 | got2a | ENSDARP00000028137 | ENSDARP00000060165 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.926 |
adss2 | got2b | ENSDARP00000028137 | ENSDARP00000024560 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.926 |
adss2 | nat8l | ENSDARP00000028137 | ENSDARP00000112150 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | N-acetylaspartate synthetase; May play a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. May promote dopamine uptake by regulating TNF-alpha expression (By similarity). | 0.900 |
asns | adss2 | ENSDARP00000107713 | ENSDARP00000028137 | Asparagine synthetase [glutamine-hydrolyzing]. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | 0.934 |
asns | aspa | ENSDARP00000107713 | ENSDARP00000068606 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.902 |
asns | asrgl1 | ENSDARP00000107713 | ENSDARP00000033788 | Asparagine synthetase [glutamine-hydrolyzing]. | Isoaspartyl peptidase/L-asparaginase alpha chain; Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. | 0.955 |
asns | cad | ENSDARP00000107713 | ENSDARP00000127377 | Asparagine synthetase [glutamine-hydrolyzing]. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.931 |
asns | got1 | ENSDARP00000107713 | ENSDARP00000129948 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartate aminotransferase. | 0.958 |
asns | got1l1 | ENSDARP00000107713 | ENSDARP00000070190 | Asparagine synthetase [glutamine-hydrolyzing]. | Glutamic-oxaloacetic transaminase 1-like 1. | 0.958 |
asns | got2a | ENSDARP00000107713 | ENSDARP00000060165 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartate aminotransferase. | 0.972 |
asns | got2b | ENSDARP00000107713 | ENSDARP00000024560 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartate aminotransferase. | 0.967 |
asns | nat8l | ENSDARP00000107713 | ENSDARP00000112150 | Asparagine synthetase [glutamine-hydrolyzing]. | N-acetylaspartate synthetase; May play a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. May promote dopamine uptake by regulating TNF-alpha expression (By similarity). | 0.928 |
aspa | adss2 | ENSDARP00000068606 | ENSDARP00000028137 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | 0.900 |
aspa | asns | ENSDARP00000068606 | ENSDARP00000107713 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate; Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.902 |