STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sptbSpectrin beta chain; Belongs to the spectrin family. (2357 aa)    
Predicted Functional Partners:
sptan1
Spectrin alpha, non-erythrocytic 1.
   
0.827
epb41b
Erythrocyte membrane protein band 4.1 (Elliptocytosis 1, RH-linked).
   
 
 0.729
ank1b
Ankyrin 1, erythrocytic b.
   
 0.687
alas2
5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
   
  
 0.676
frrs1a
Ferric-chelate reductase 1a.
      
 0.645
LOC100534669
Uncharacterized protein.
      
 0.619
slc4a1a
Anion exchange protein.
   
  
 0.573
sphkap
A-kinase anchor protein SPHKAP; Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).
   
  
 0.556
frrs1b
Ferric-chelate reductase 1b.
      
 0.541
dapp1
Dual adaptor of phosphotyrosine and 3-phosphoinositides.
      
 0.540
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.