node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abhd2b | cd74a | ENSDARP00000067326 | ENSDARP00000002547 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.479 |
abhd2b | lyrm5b | ENSDARP00000067326 | ENSDARP00000113978 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.744 |
abhd2b | mid1ip1b | ENSDARP00000067326 | ENSDARP00000021980 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.743 |
abhd2b | mthfd1l | ENSDARP00000067326 | ENSDARP00000061913 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like. | 0.540 |
abhd2b | nt5c2l1 | ENSDARP00000067326 | ENSDARP00000020283 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 5'-nucleotidase, cytosolic II,-like 1. | 0.479 |
cd74a | abhd2b | ENSDARP00000002547 | ENSDARP00000067326 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.479 |
cd74a | lyrm5b | ENSDARP00000002547 | ENSDARP00000113978 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.481 |
cd74a | mid1ip1b | ENSDARP00000002547 | ENSDARP00000021980 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.533 |
etfa | etfb | ENSDARP00000140482 | ENSDARP00000017410 | Electron-transfer-flavoprotein, alpha polypeptide. | Electron transfer flavoprotein subunit beta. | 0.999 |
etfa | lyrm5b | ENSDARP00000140482 | ENSDARP00000113978 | Electron-transfer-flavoprotein, alpha polypeptide. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.671 |
etfa | ndufab1a | ENSDARP00000140482 | ENSDARP00000075780 | Electron-transfer-flavoprotein, alpha polypeptide. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.748 |
etfa | ndufab1b | ENSDARP00000140482 | ENSDARP00000012558 | Electron-transfer-flavoprotein, alpha polypeptide. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.731 |
etfa | palb2 | ENSDARP00000140482 | ENSDARP00000100652 | Electron-transfer-flavoprotein, alpha polypeptide. | Partner and localizer of BRCA2. | 0.690 |
etfb | etfa | ENSDARP00000017410 | ENSDARP00000140482 | Electron transfer flavoprotein subunit beta. | Electron-transfer-flavoprotein, alpha polypeptide. | 0.999 |
etfb | lyrm5b | ENSDARP00000017410 | ENSDARP00000113978 | Electron transfer flavoprotein subunit beta. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.511 |
etfb | ndufab1a | ENSDARP00000017410 | ENSDARP00000075780 | Electron transfer flavoprotein subunit beta. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.563 |
etfb | ndufab1b | ENSDARP00000017410 | ENSDARP00000012558 | Electron transfer flavoprotein subunit beta. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.566 |
etfb | palb2 | ENSDARP00000017410 | ENSDARP00000100652 | Electron transfer flavoprotein subunit beta. | Partner and localizer of BRCA2. | 0.515 |
lyrm5b | abhd2b | ENSDARP00000113978 | ENSDARP00000067326 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.744 |
lyrm5b | cd74a | ENSDARP00000113978 | ENSDARP00000002547 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.481 |