STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSDARG00000032838Si:dkey-206f10.1 (1187 aa)    
Predicted Functional Partners:
prkacab
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
   
 0.883
pde10a
Phosphodiesterase 10A
   
 0.875
pde1a
Phosphodiesterase 1A, calmodulin-dependent
   
 
 0.854
prkacaa
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
   
 0.829
ENSDARG00000044537
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases
  
 0.774
pde4a
Phosphodiesterase 4A, cAMP-specific
   
 0.773
pde6b
Phosphodiesterase 6B, cGMP-specific, rod, beta
   
 0.755
prkacba
Protein kinase, cAMP-dependent, catalytic, beta a
   
 0.752
ENSDARG00000087866
Protein kinase, cAMP-dependent, catalytic, beta b
   
 0.752
rapgef3
Rap guanine nucleotide exchange factor (GEF) 3
   
 
 0.746
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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