STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
c4bComplement 4B (Chido blood group). (1725 aa)    
Predicted Functional Partners:
cfi
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.892
c1r
Complement component 1, r subcomponent; Belongs to the peptidase S1 family.
   
 0.830
c4
Complement component 4.
  
 
 
0.823
cfb
Complement factor B; Belongs to the peptidase S1 family.
   
 0.787
C3AR1
C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family.
    
 
 0.752
rca2.1
Regulator of complement activation group 2 gene 1.
    
 
 0.727
F1QJB3_DANRE
Si:ch1073-280e3.1; Belongs to the peptidase S1 family.
   
 0.705
masp2
Mannan-binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.690
hbl1
Zmp:0000000729.
    
 0.683
masp1
Mannan-binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
    
 0.663
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.