STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr19-2Toll-like receptor 19. (920 aa)    
Predicted Functional Partners:
lenep
Lens epithelial protein.
      
 0.743
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response.
   
 
 0.742
frmpd1a
FERM and PDZ domain-containing 1a.
      
 0.738
ticam1
Toll-like receptor adaptor molecule 1.
   
 
 0.736
unc93b1
Unc-93 homolog B1, TLR-signaling regulator.
    
 
 0.719
traf6
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.
   
 
 0.696
pbxip1b
Pre-B-cell leukemia homeobox-interacting protein 1b.
    
 
 0.673
tirap
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein.
   
 
 0.666
gcna
Germ cell nuclear acidic peptidase.
      
 0.647
irak4
Interleukin-1 receptor-associated kinase 4.
   
 
 0.613
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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