STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chrneCholinergic receptor, nicotinic, epsilon. (517 aa)    
Predicted Functional Partners:
chrna1
Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  
0.897
colq
Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase.
    
 
 0.865
dok7
Docking protein 7.
   
  
 0.861
rapsn
Receptor-associated protein of the synapse, 43kD.
   
 
 0.860
musk
Muscle, skeletal, receptor tyrosine kinase.
   
 
 0.843
chrna4b
Neuronal nicotinic acetylcholine receptor alpha 4 subunit.
  
 
0.802
chrna2a
Cholinergic receptor, nicotinic, alpha 2a (neuronal).
  
 
 
0.794
chrna7
Cholinergic receptor, nicotinic, alpha 7 (neuronal).
   
0.773
chrnb1
Cholinergic receptor, nicotinic, beta 1 (muscle).
  
 
0.758
gfpt1
Glutamine--fructose-6-phosphate transaminase 1.
      
 0.742
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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