node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
enpp1 | itpa | ENSDARP00000112341 | ENSDARP00000074674 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.911 |
enpp1 | mocs1 | ENSDARP00000112341 | ENSDARP00000099913 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Molybdenum cofactor synthesis 1. | 0.811 |
enpp1 | npr1a | ENSDARP00000112341 | ENSDARP00000116998 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Guanylate cyclase. | 0.906 |
enpp1 | npr1b | ENSDARP00000112341 | ENSDARP00000010052 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Guanylate cyclase. | 0.906 |
enpp1 | nudt2 | ENSDARP00000112341 | ENSDARP00000076102 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 2. | 0.909 |
enpp1 | pde5ab | ENSDARP00000112341 | ENSDARP00000114140 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Phosphodiesterase. | 0.907 |
enpp1 | pde6b | ENSDARP00000112341 | ENSDARP00000123023 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Phosphodiesterase. | 0.925 |
enpp1 | pde6gb | ENSDARP00000112341 | ENSDARP00000134212 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. | 0.900 |
itpa | enpp1 | ENSDARP00000074674 | ENSDARP00000112341 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.911 |
itpa | mocs1 | ENSDARP00000074674 | ENSDARP00000099913 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Molybdenum cofactor synthesis 1. | 0.800 |
itpa | npr1a | ENSDARP00000074674 | ENSDARP00000116998 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Guanylate cyclase. | 0.901 |
itpa | npr1b | ENSDARP00000074674 | ENSDARP00000010052 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Guanylate cyclase. | 0.901 |
itpa | nudt2 | ENSDARP00000074674 | ENSDARP00000076102 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Nudix (nucleoside diphosphate-linked moiety X)-type motif 2. | 0.935 |
itpa | pde5ab | ENSDARP00000074674 | ENSDARP00000114140 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Phosphodiesterase. | 0.903 |
itpa | pde6b | ENSDARP00000074674 | ENSDARP00000123023 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Phosphodiesterase. | 0.900 |
itpa | pde6gb | ENSDARP00000074674 | ENSDARP00000134212 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. | 0.900 |
mocs1 | enpp1 | ENSDARP00000099913 | ENSDARP00000112341 | Molybdenum cofactor synthesis 1. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.811 |
mocs1 | itpa | ENSDARP00000099913 | ENSDARP00000074674 | Molybdenum cofactor synthesis 1. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.800 |
mocs1 | npr1a | ENSDARP00000099913 | ENSDARP00000116998 | Molybdenum cofactor synthesis 1. | Guanylate cyclase. | 0.831 |
mocs1 | npr1b | ENSDARP00000099913 | ENSDARP00000010052 | Molybdenum cofactor synthesis 1. | Guanylate cyclase. | 0.830 |