STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cox14Cytochrome c oxidase assembly protein COX14 homolog; Plays a role in the assembly or stability of the cytochrome c oxidase complex (COX). (97 aa)    
Predicted Functional Partners:
higd2a
HIG1 hypoxia-inducible domain family, member 2A.
   
  
 0.953
gatd3a
Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial.
      
 0.893
coa3a
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial; Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
   
 
 0.877
atp5md
ATP synthase membrane subunit DAPIT.
   
  
 0.822
higd1a
HIG1 hypoxia-inducible domain family, member 1A.
   
  
 0.788
coa3b
Cytochrome C oxidase assembly factor 3b.
   
 
 0.769
romo1
Reactive oxygen species modulator 1; Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage (By similarity).
   
  
 0.758
es1
ES1 protein, mitochondrial; Plays a role in promoting mitochondrial enlargement in cone photoreceptor cells in a fusion-independent and ATP-dependent manner.
      
 0.750
uqcr10
Ubiquinol-cytochrome c reductase, complex III subunit X.
   
    0.720
ndufs5
NADH dehydrogenase (Ubiquinone) Fe-S protein 5.
   
    0.719
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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