STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adgrb2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (635 aa)    
Predicted Functional Partners:
ftr52p
FinTRIM family, member 52, pseudogene.
   
 
 0.937
RANBP2
Si:ch1073-55a19.2.
   
 
 0.937
adgrg3
Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family.
      
 0.745
tmem82
Transmembrane protein 82.
      
 0.744
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4.
   
  
 0.739
kpnb1
Karyopherin (importin) beta 1.
   
 
 0.734
adgrv1
Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system.
      
 0.721
xpot
Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. Belongs to the exportin family.
   
 
 0.713
rangrf
Ran guanine nucleotide release factor; May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP. Plays a role in the regulation of the levels of GTP-bound RAN in the nucleus (By similarity). Required for normal expression of the ion channel hcn4 and for normal expression of the cardiac transcription factors nkx2.5, gata4 and hand2 during embryonic development. Required for normal embryonic heart development and normal heart rate.
    
 
 0.696
nup153
Nucleoporin 153.
    
 
 0.681
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.