STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glipr2GLI pathogenesis-related 2; Belongs to the CRISP family. (543 aa)    
Predicted Functional Partners:
gart
Phosphoribosylglycinamide formyltransferase.
    
  0.869
tril
TLR4 interactor with leucine-rich repeats.
      
 0.744
pcdh11
Protocadherin 11.
      
 0.664
pcdh11-2
Protocadherin 11.
      
 0.664
cdh31
Cadherin 31; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.579
il22ra2
Interleukin 22 receptor, alpha 2.
   
  
 0.563
tspan1
Tetraspanin.
      
 0.554
myo15aa
Myosin XVAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.546
ptpn22
Protein tyrosine phosphatase non-receptor type 22.
   
  
 0.512
ripply1
Protein ripply1; Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites.
      
 0.500
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.