STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osgepProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity; Belongs to the KAE1 / TsaD family. (335 aa)    
Predicted Functional Partners:
tprkb
EKC/KEOPS complex subunit TPRKB; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Tprkb acts as an allosteric effector that regulates the t(6)A activity of the complex. Belongs to the CGI121/TPRKB family.
   
 0.999
lage3
Uncharacterized protein.
   
 0.999
tp53rk
TP53-regulating kinase.
  
 0.999
acp1
Acid phosphatase 1.
  
 
 0.865
yrdc
YrdC N(6)-threonylcarbamoyltransferase domain-containing.
  
 
 0.806
F1QWR2_DANRE
Si:ch211-153b23.4.
  
 
 0.796
ENSDARP00000129937
Si:ch211-153b23.3.
  
 
 0.796
wdr73
WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics; Belongs to the WD repeat WDR73 family.
   
  
 0.743
eprs1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.710
coasy
CoA synthase.
    
 0.689
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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