STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
calcrlaCalcitonin gene-related peptide type 1 receptor; Receptor for calcitonin-gene-related peptide (CGRP) (By similarity). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity); Belongs to the G-protein coupled receptor 2 family. (474 aa)    
Predicted Functional Partners:
ramp2
Receptor (G protein-coupled) activity-modifying protein 2.
   
 0.996
RAMP1
Zgc:91818 protein.
    
 0.996
adma
Adrenomedullin a.
    
 0.996
calca
Calcitonin/calcitonin-related polypeptide, alpha.
   
 0.987
F1QAN5_DANRE
Si:ch73-334d15.2.
    
 0.953
iapp
CALCITONIN domain-containing protein.
    
 0.918
calcrl2
G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family.
  
  
0.905
RAMP3
Receptor activity modifying protein 3.
    
 
 0.904
calcrlb
Calcitonin receptor-like b; Belongs to the G-protein coupled receptor 2 family.
  
  
0.903
adm2a
Adrenomedullin 2a.
    
 
 0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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