STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coa5Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process. (75 aa)    
Predicted Functional Partners:
mrpl51
39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family.
   
  
 0.978
MRPL49
Mitochondrial ribosomal protein L49.
   
  
 0.974
mrpl20
Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family.
   
  
 0.961
timm9
Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family.
   
  
 0.938
mrpl48
Mitochondrial ribosomal protein L48.
   
  
 0.875
cox17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae).
   
  
 0.811
txndc9
Thioredoxin domain-containing 9.
      
 0.804
dmac2l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s.
   
  
 0.752
hsbp1a
Heat shock factor-binding protein 1a.
      
 0.719
gfer
Sulfhydryl oxidase.
   
  
 0.704
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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