STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
zdhhc16aPalmitoyltransferase ZDHHC16A; Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway. (387 aa)    
Predicted Functional Partners:
zdhhc21
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.868
lypla2
Lysophospholipase 2.
      
 0.762
selenok
Selenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Required for palmitoylation (By similarity). Belongs to the selenoprotein K family.
   
  
 0.627
golga7
Golgin A7.
      
 0.596
dlg2
Disks large homolog 2; May play a role in synapse assembly and function.
   
  
 0.557
golga7ba
Golgin A7 family, member Ba.
   
  
 0.518
ubtd1a
Ubiquitin domain-containing 1a.
      
 0.507
ubtd1b
Ubiquitin domain-containing protein 1; May be involved in the regulation of cellular senescence through a positive feedback loop with TP53.
      
 0.507
zdhhc13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
0.491
zdhhc17
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
0.482
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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