node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccnh | cdk2 | ENSDARP00000004735 | ENSDARP00000032448 | Cyclin H; Belongs to the cyclin family. | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. | 0.988 |
ccnh | cdk7 | ENSDARP00000004735 | ENSDARP00000051002 | Cyclin H; Belongs to the cyclin family. | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | 0.999 |
ccnh | ercc2 | ENSDARP00000004735 | ENSDARP00000114026 | Cyclin H; Belongs to the cyclin family. | Excision repair cross-complementation group 2. | 0.997 |
ccnh | ercc3 | ENSDARP00000004735 | ENSDARP00000010637 | Cyclin H; Belongs to the cyclin family. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.984 |
ccnh | gtf2e1 | ENSDARP00000004735 | ENSDARP00000001151 | Cyclin H; Belongs to the cyclin family. | General transcription factor IIE, polypeptide 1, alpha. | 0.995 |
ccnh | gtf2e2 | ENSDARP00000004735 | ENSDARP00000020885 | Cyclin H; Belongs to the cyclin family. | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | 0.994 |
ccnh | gtf2h1 | ENSDARP00000004735 | ENSDARP00000038901 | Cyclin H; Belongs to the cyclin family. | General transcription factor IIH, polypeptide 1. | 0.988 |
ccnh | gtf2h3 | ENSDARP00000004735 | ENSDARP00000088015 | Cyclin H; Belongs to the cyclin family. | General transcription factor IIH, polypeptide 3. | 0.998 |
ccnh | gtf2h4 | ENSDARP00000004735 | ENSDARP00000052358 | Cyclin H; Belongs to the cyclin family. | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. | 0.981 |
ccnh | mnat1 | ENSDARP00000004735 | ENSDARP00000027502 | Cyclin H; Belongs to the cyclin family. | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. | 0.999 |
cdk2 | ccnh | ENSDARP00000032448 | ENSDARP00000004735 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. | Cyclin H; Belongs to the cyclin family. | 0.988 |
cdk2 | cdk7 | ENSDARP00000032448 | ENSDARP00000051002 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | 0.946 |
cdk2 | mnat1 | ENSDARP00000032448 | ENSDARP00000027502 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. | 0.550 |
cdk7 | ccnh | ENSDARP00000051002 | ENSDARP00000004735 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | Cyclin H; Belongs to the cyclin family. | 0.999 |
cdk7 | cdk2 | ENSDARP00000051002 | ENSDARP00000032448 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. | 0.946 |
cdk7 | ercc2 | ENSDARP00000051002 | ENSDARP00000114026 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | Excision repair cross-complementation group 2. | 0.961 |
cdk7 | ercc3 | ENSDARP00000051002 | ENSDARP00000010637 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.965 |
cdk7 | gtf2e1 | ENSDARP00000051002 | ENSDARP00000001151 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | General transcription factor IIE, polypeptide 1, alpha. | 0.916 |
cdk7 | gtf2e2 | ENSDARP00000051002 | ENSDARP00000020885 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | 0.934 |
cdk7 | gtf2h1 | ENSDARP00000051002 | ENSDARP00000038901 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. | General transcription factor IIH, polypeptide 1. | 0.943 |